Stephen J. Schueler, M.D.

Heart Failure Nitrates

These drugs are useful in the care of congestive heart failure due to coronary artery disease. A regular schedule of nitrates can help to decrease the incidence of anginal attacks and control blood pressure.

Nitrates dilate the veins encouraging blood to more readily return to the heart. They also open up the arteries that supply the heart itself. Both of these effects work together to reduce the heart muscles demand for oxygen and increase its supply.

Nitrates:

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Last Updated: Dec 8, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Heart Failure References
  1. Bibbins-Domingo K, Lin F, Vittinghoff E, Barrett-Connor E, Hulley SB, Grady D, Shlipak MG. Predictors of heart failure among women with coronary disease. Circulation. 2004 Sep 14;110(11):1424-30. [1535349]
  2. Chen QM, Tu VC. Apoptosis and heart failure: mechanisms and therapeutic implications. Am J Cardiovasc Drugs. 2002;2(1):43-57. [14727998]
  3. Ebinger MW, Krishnan S, Schuger CD. Mechanisms of ventricular arrhythmias in heart failure. Curr Heart Fail Rep. 2005 Sep;2(3):111-7. [16138946]
  4. Mitchell J, Taylor A. Congestive heart failure in women. J Fam Pract. 2005 Jul;Suppl:6-7. [16134558]
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