Heart Chest Pain Thrombolytics
Coronary arteries become narrowed when cholesterol builds up on the inside wall of the artery. If a clot forms where the artery is narrowed, then the artery becomes completely blocked, causing angina or a heart attack. Thrombolytic medications are powerful blood thinners that can break down new blood clots in the coronary arteries.
Thrombolytic medications include:
- Alteplase, (t-PA, Activase)
- Reteplase (Retavase)
- Anistreplase (Eminase)
- Streptokinase (Kabikinase, Streptase)
- Tissue plasminogen activator
- Tenecteplase (TNKase)
Severe bleeding is the major complication of the thrombolytic medications. Overall, they reduce the risk of death from a heart attack.
Conditions in which thrombolytics are not used include:
Continue to Heart Chest Pain Long-Term Care
- Abrams J. Clinical practice. Chronic stable angina. N Engl J Med. 2005 Jun 16;352(24):2524-33. 
- Brown TL, Merrill J, Hill P, Bengel FM. Relationship of coronary calcium and myocardial perfusion in individuals with chest pain. Assessed by integrated rubidium-82 PET-CT. Nuklearmedizin. 2008;47(6):255-260. 
- O'Toole L. Angina (stable). Clin Evid. 2005 Jun;(13):62-9. 
- Parker JO. Angina pectoris: a review of current and emerging therapies. Am J Manag Care. 2004 Oct;10(11 Suppl):S332-8. 
- Scheidt S. Treatment of stable angina: medical and invasive therapy--implications for the elderly. Am J Geriatr Cardiol. 2005 Jul-Aug;14(4):183-92.