Stephen J. Schueler, M.D.

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Grave's Disease Underlying Cause

Grave's disease is caused by a malfunction in the immune system, which normally fights infection. For some reason, the immune system mistakenly stimulates the thyroid gland, causing it to swell and produce high levels of thyroid hormones. The cause for the immune system malfunction is unknown.

Continue to Grave's Disease Anatomy

Last Updated: Apr 28, 2008 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Grave's Disease References
  1. Abraham P, Avenell A, Watson WA, Park CM, Bevan JS. Antithyroid drug regimen for treating Graves' hyperthyroidism. Cochrane Database Syst Rev. 2005 Apr 18;(2):CD003420. [15846664]
  2. Holm IA, Manson JE, Michels KB, Alexander EK, Willett WC, Utiger RD. Smoking and other lifestyle factors and the risk of Graves' hyperthyroidism. Arch Intern Med. 2005 Jul 25;165(14):1606-11. [16043678]
  3. McKeown NJ, Tews MC, Gossain VV, Shah SM. Hyperthyroidism. Emerg Med Clin North Am. 2005 Aug;23(3):669-85, viii. [15982540]
  4. Weetman AP. Grave's disease 1835-2002. Horm Res. 2003;59 Suppl 1:114-8. [12638522]
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