Stephen J. Schueler, M.D.

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Grand Mal Seizure Underlying Cause

A seizure is a sudden, abnormal discharge of electrical activity in the brain. During a tonic clonic seizure, the electrical impulses spread throughout the brain. This stimulates the brain to send uncontrolled signals to the rest of the body.

There are many conditions that either increase the risk of having seizures or directly cause them.

Common causes of seizures include:

Less common causes of seizures include:

Continue to Grand Mal Seizure Anatomy

Last Updated: Feb 10, 2011 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Grand Mal Seizure References
  1. Camfield P, Camfield C. Epileptic syndromes in childhood: clinical features, outcomes, and treatment. Epilepsia. 2002;43 Suppl 3:27-32. [12060004]
  2. Gilad R, Lampl Y, Gabbay U, Eshel Y, Sarova-Pinhas I. Early treatment of a single generalized tonic-clonic seizure to prevent recurrence. Arch Neurol. 1996 Nov;53(11):1149-52. [8912488]
  3. Kinsman SL, Vining EP, Quaskey SA, Mellits D, Freeman JM. Efficacy of the ketogenic diet for intractable seizure disorders: review of 58 cases. Epilepsia. 1992 Nov-Dec;33(6):1132-6. [1464275]
  4. Pearl PL, Bennett HD, Khademian Z. Seizures and metabolic disease. Curr Neurol Neurosci Rep. 2005 Mar;5(2):127-33. [15743550]
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