What is a glucagonoma?
A person with a glucagonoma has a very rare malignant tumor that can develop in the islet cells of the pancreas. About 50% of malignant glucagonomas have spread outside of the pancreas at the time of diagnosis. These tumors are discovered because they release the hormones insulin and glucagon. These hormones are responsible for many of the symptoms of glucagonoma syndrome. Another important feature of glucagonoma syndrome is a very high risk for pulmonary embolism.
What are the symptoms of a glucagonoma?
The symptoms of a glucagonoma include diarrhea, excessive thirst, inflammation of the mouth and tongue, nighttime enuresis, frequent urination, and a skin rash on the face, abdomen, buttocks and legs that comes and goes.
How does the doctor treat a glucagonoma?
The treatment for a glucagonoma includes surgery to remove the tumor. Medications that have been used to treat glucagonoma include octreotide (Sandostatin), doxorubicin (Adriamycin, Rubex), fluorouracil (Adrucil), streptozocin (Zanosar), and dacarbazine (DTIC-Dome).
Continue to Glucagonoma Symptoms
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