Stephen J. Schueler, M.D.

Glioma Underlying Cause

The cause of glioma is unknown, but genetics may play a role in determining risk.

Genes control the functions inside a cell. Special genes control how cells divide and grow. Cancer occurs when the damaged genes stimulate the cell to multiply out of control. The exact cause for this damage is unknown.

Examples:

  • DNA
  • Genes on chromosomes
  • Cancer cells
  • Cancer cell division

Brain tumors cause damage by causing swelling, by placing pressure against parts of the brain, or by increasing pressure inside the skull.

Continue to Glioma Types

Last Updated: Sep 25, 2008 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Glioma References
  1. Laperriere N, Zuraw L, Cairncross G; Cancer Care Ontario Practice Guidelines Initiative Neuro-Oncology Disease Site Group. Radiotherapy for newly diagnosed malignant glioma in adults: a systematic review. Radiother Oncol. 2002 Sep;64(3):259-73. [12242114]
  2. Salvati M, Caroli E, Orlando ER, Frati A, Artizzu S, Ferrante L. Multicentric glioma: our experience in 25 patients and critical review of the literature. Neurosurg Rev. 2003 Oct;26(4):275-9. [12898393]
  3. Stewart LA. Chemotherapy in adult high-grade glioma: a systematic review and meta-analysis of individual patient data from 12 randomised trials. Lancet. 2002 Mar 23;359(9311):1011-8. [11937180]
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