Gastric Ulcer Drugs
Treatment for peptic ulcer disease usually requires killing the Helicobacter pylori bacteria in the stomach. This is accomplished by taking a combination of antibiotics and acid-blocking drugs. The antibiotics must be taken for 14 days. The acid-blocking medication is usually taken for at least 4 weeks. Your doctor will determine which of the following combinations is best for you.
One of the following antibiotic combination options:
- 14 days of clarithromycin (Biaxin) and amoxicillin (Amoxil, Trimox)
- 14 days of metronidazole (Flagyl) and amoxicillin (Amoxil, Trimox)
- 14 days of metronidazole (Flagyl) and tetracycline (Sumycin)
One of the following acid-blocking medication options:
- Proton pump inhibitor medications:
The most commonly prescribed combination of medication used to treat peptic ulcer disease includes:
If one of the above treatment combinations fails, quadruple drug therapy may be used to treat peptic ulcer disease:
Continue to Gastric Ulcer Questions For Doctor
- Bodger K, Daly MJ, Heatley RV. Clinical economics review: Helicobacter pylori-associated peptic ulcer disease. Aliment Pharmacol Ther. 1997 Apr;11(2):273-82. 
- Ford A, Delaney B, Forman D, Moayyedi P. Eradication therapy for peptic ulcer disease in Helicobacter pylori positive patients. Cochrane Database Syst Rev. 2004 Oct 18;(4):CD003840. 
- Ford AC, Delaney BC, Forman D, Moayyedi P. Eradication therapy in Helicobacter pylori positive peptic ulcer disease: systematic review and economic analysis. Am J Gastroenterol. 2004 Sep;99(9):1833-55. 
- Vakil N, Fennerty MB. Direct comparative trials of the efficacy of proton pump inhibitors in the management of gastro-oesophageal reflux disease and peptic ulcer disease. Aliment Pharmacol Ther. 2003 Sep 15;18(6):559-68.