Foot Friction Blister Underlying Cause
A blister forms when fluid collects under the superficial layer of skin, called the epidermis. Blood vessels leak fluid into the space under the epidermis when the skin is injured or irritated.
Common causes of skin blisters include:
- Friction injury
- Contact dermatitis:
- Drug reactions
- Insect bites
- Jellyfish stings
- Herpes simplex infections:
- Other viral infections:
Less common causes of skin blisters include:
Continue to Foot Friction Blister Anatomy
- Buchman JS. Blistering diseases of the skin. Clin Podiatr Med Surg. 1996 Jan;13(1):91-108. 
- Cotell S, Robinson ND, Chan LS. Autoimmune blistering skin diseases. Am J Emerg Med. 2000 May;18(3):288-99. 
- Diaz LA, Giudice GJ. End of the century overview of skin blisters. Arch Dermatol. 2000 Jan;136(1):106-12.