Stephen J. Schueler, M.D.

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Factor 7 Deficiency Underlying Cause

Normal blood clotting requires the complex interaction of about 20 different blood proteins. Many of these proteins are manufactured in the liver and are regulated by the activities of enzymes and other cofactors.

Factor 7 deficiency is an inherited illness. Low levels of this clotting factor result in prolonged blood clotting. Factor 7 deficiency can occur in women as well as men.

Last Updated: Dec 10, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Factor 7 Deficiency References
  1. Barnett JM, Demel KC, Mega AE, Butera JN, Sweeney JD. Lack of bleeding in patients with severe factor VII deficiency. Am J Hematol. 2005 Feb;78(2):134-7. [15682417]
  2. Brummel Ziedins K, Rivard GE, Pouliot RL, Butenas S, Gissel M, Parhami-Seren B, Mann KG. Factor VIIa replacement therapy in factor VII deficiency. J Thromb Haemost. 2004 Oct;2(10):1735-44. [15456484]
  3. Muntean W. Fresh frozen plasma in the pediatric age group and in congenital coagulation factor deficiency. Thromb Res. 2002 Oct 31;107 Suppl 1:S29-32. [12379290]
  4. Perry DJ. Factor VII deficiency. Blood Coagul Fibrinolysis. 2003 Jun;14 Suppl 1:S47-54. [14567537]
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