Factor 7 Deficiency Overview
What is factor 7 deficiency?
A person with factor 7 deficiency has a rare, hereditary blood clotting disorder that can result in severe bleeding. Normal blood coagulation requires the complex interaction of about 20 proteins, called clotting factors. Low levels of factor 7 result in prolonged blood clotting.
What are the symptoms of factor 7 deficiency?
Symptoms of factor 7 deficiency include bleeding into the joints, joint swelling, joint pain, bleeding gums, nosebleeds, and easy bruising. Women may experience heavy menstrual periods.
How does the doctor treat factor 7 deficiency?
There is no cure for factor 7 deficiency. Treatment for factor 7 deficiency may include fresh frozen plasma, factor 7 concentrate, and vitamin K. Patients should avoid aspirin, nonsteroidal anti-inflammatory medications, and other medications that can promote bleeding.
Continue to Factor 7 Deficiency Symptoms
- Barnett JM, Demel KC, Mega AE, Butera JN, Sweeney JD. Lack of bleeding in patients with severe factor VII deficiency. Am J Hematol. 2005 Feb;78(2):134-7. 
- Brummel Ziedins K, Rivard GE, Pouliot RL, Butenas S, Gissel M, Parhami-Seren B, Mann KG. Factor VIIa replacement therapy in factor VII deficiency. J Thromb Haemost. 2004 Oct;2(10):1735-44. 
- Muntean W. Fresh frozen plasma in the pediatric age group and in congenital coagulation factor deficiency. Thromb Res. 2002 Oct 31;107 Suppl 1:S29-32. 
- Perry DJ. Factor VII deficiency. Blood Coagul Fibrinolysis. 2003 Jun;14 Suppl 1:S47-54.