FreeMD® Factor 12 Deficiency Underlying Cause

Factor 12 Deficiency

Underlying Cause

Factor 12 Deficiency Underlying Cause

Normal blood clotting requires the complex interaction of about 20 different blood proteins. Many of these proteins are manufactured in the liver and are regulated by the activities of enzymes and other cofactors.

Factor 12 deficiency is an inherited illness. Low levels of this clotting factor do not result in prolonged blood clotting.

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Related Conditions

Anticoagulant medication bleeding
Factor 10 deficiency
Factor 2 deficiency
Factor 5 deficiency
Factor 7 deficiency
Hemophilia
Platelet function disorder
Von Willebrand's disease

Bleeding gums
Excessive bleeding
Excessive bruising
Nosebleed

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Last Updated: May 29, 2009 References

Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD

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Factor 12 Deficiency References:

Baker WF Jr, Bick RL. Treatment of hereditary and acquired thrombophilic disorders. Semin Thromb Hemost. 1999;25(4):387-406.
Girolami A, Simioni P, Scarano L, Girolami B, Zerbinati P. Symptomatic combined homozygous factor XII deficiency and heterozygous factor V Leiden. J Thromb Thrombolysis. 2000 Apr;9(3):271-5.
Muntean W. Fresh frozen plasma in the pediatric age group and in congenital coagulation factor deficiency. Thromb Res. 2002 Oct 31;107 Suppl 1:S29-32.