Factor 10 Deficiency Underlying Cause
Normal blood clotting requires the complex interaction of about 20 different blood proteins. Many of these proteins are manufactured in the liver and are regulated by the activities of enzymes and other cofactors.
Factor 10 deficiency is an inherited illness. Low levels of this clotting protein result in prolonged blood clotting. Factor 10 deficiency can occur in women as well as men.
Additional causes include:
- Baker WF Jr, Bick RL. Treatment of hereditary and acquired thrombophilic disorders. Semin Thromb Hemost. 1999;25(4):387-406. 
- McMahon C, Smith J, Goonan C, Byrne M, Smith OP. The role of primary prophylactic factor replacement therapy in children with severe factor X deficiency. Br J Haematol. 2002 Dec;119(3):789-91. 
- Muntean W. Fresh frozen plasma in the pediatric age group and in congenital coagulation factor deficiency. Thromb Res. 2002 Oct 31;107 Suppl 1:S29-32. 
- Uprichard J, Perry DJ. Factor X deficiency. Blood Rev. 2002 Jun;16(2):97-110.