Stephen J. Schueler, M.D.

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Epidermolysis Bullosa Overview

What is epidermolysis bullosa?
A person with epidermolysis bullosa has abnormal blistering and peeling of the skin that occurs after a minor skin injury. Epidermolysis bullosa is an inherited disorder that causes weakness of the superficial layers of the skin. Open blisters and peeling skin disrupt the normal barrier to infection, increasing the risk of skin infections. Severe blisters and peeling of the hands and feet can result in disability.

What are the symptoms of epidermolysis bullosa?
Symptoms of epidermolysis bullosa include large blisters that may be triggered by skin injury or skin rubbing. Blisters may peel.

How does the doctor treat epidermolysis bullosa?
Treatment for epidermolysis bullosa includes skin injury prevention, gentle skin cleansing and the application of antibiotic ointment. Other measures include protective bandages, whirlpool, skin grafts, and medications for pain.

Continue to Epidermolysis Bullosa Incidence

Last Updated: Feb 8, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Epidermolysis Bullosa References
  1. Lim KK, Su WP, McEvoy MT, Pittelkow MR. Generalized gravis junctional epidermolysis bullosa: case report, laboratory evaluation, and review of recent advances. Mayo Clin Proc. 1996 Sep;71(9):863-8. [8790263 ]
  2. Ozanic Bulic S, Fassihi H, Mellerio JE, McGrath JA, Atherton DJ. Thalidomide in the management of epidermolysis bullosa pruriginosa. Br J Dermatol. 2005 Jun;152(6):1332-4. [15949003]
  3. Vodegel RM, de Jong MC, Pas HH, Jonkman MF. IgA-mediated epidermolysis bullosa acquisita: two cases and review of the literature. J Am Acad Dermatol. 2002 Dec;47(6):919-25. [12451379]
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