Stephen J. Schueler, M.D.

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Dubin Johnson Syndrome Overview

What is Dubin Johnson syndrome?
A person with Dubin Johnson syndrome has a rare inherited disorder that causes the buildup of bilirubin in the liver, resulting in episodes of mild jaundice. Bilirubin is one of the by-products that result from the breakdown of hemoglobin, which carries oxygen in the bloodstream. The episodes of jaundice are temporary and treatment is not required. Those with Dubin Johnson syndrome live normal lives and have a normal life expectancy.

What are the symptoms of Dubin Johnson syndrome?
Symptoms of Dubin Johnson syndrome include mild jaundice, brown urine, and clay-colored stools.

How does the doctor treat Dubin Johnson syndrome?
Treatment for Dubin Johnson syndrome is not required. The jaundice resolves without treatment.

Continue to Dubin Johnson Syndrome Symptoms

Last Updated: Feb 8, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Dubin Johnson Syndrome References
  1. Haimi-Cohen Y, Amir J, Merlob P. Neonatal and infantile Dubin-Johnson syndrome. Pediatr Radiol. 1998 Nov;28(11):900. [979933]
  2. Regev RH, Stolar O, Raz A, Dolfin T. Treatment of severe cholestasis in neonatal Dubin-Johnson syndrome with ursodeoxycholic acid. J Perinat Med. 2002;30(2):185-7. [12012642]
  3. Teh CP, Nevard CH, Lawson N. Clinical quiz. Dubin-Johnson syndrome or Rotor syndrome. Pediatr Nephrol. 1999 Sep;13(7):627-8. [10507830]
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