Drug Induced SLE Underlying Cause
The exact cause of drug induced lupus is unknown. Drug induced lupus is an autoimmune disorder: for some reason, the drug causes the immune system to attack normal tissues in the body. This causes inflammation and damage to the tissue.
Drugs that can cause lupus:
- Adhami E. A predictive equation for drug-induced lupus. Med Hypotheses. 2003 Oct;61(4):473-6. 
- Rubin RL. Drug-induced lupus. Toxicology. 2005 Apr 15;209(2):135-47. 
- Uetrecht J. Current trends in drug-induced autoimmunity. Autoimmun Rev. 2005 Jun;4(5):309-14.