Stephen J. Schueler, M.D.

Depression Underlying Cause

The exact cause of depression is unknown. The brain makes chemicals, called neurotransmitters, which relay messages between brain cells. Those who have depression tend to have abnormal levels of certain neurotransmitters in the brain.

Neurotransmitter levels are affected by:

Types of depression include:

Depression Associated Conditions

Continue to Depression Types

Last Updated: Apr 4, 2011 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Depression References
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  3. Barrett B, Byford S, Knapp M. Evidence of cost-effective treatments for depression: a systematic review. J Affect Disord. 2005 Jan;84(1):1-13. [15620380]
  4. Neumeyer-Gromen A, Lampert T, Stark K, Kallischnigg G. Disease management programs for depression: a systematic review and meta-analysis of randomized controlled trials. Med Care. 2004 Dec;42(12):1211-21. [15550801]
  5. Remick RA. Diagnosis and management of depression in primary care: a clinical update and review. CMAJ. 2002 Nov 26;167(11):1253-60. [1245108]
  6. Wulsin LR. Is depression a major risk factor for coronary disease? A systematic review of the epidemiologic evidence. Harv Rev Psychiatry. 2004 Mar-Apr;12(2):79-93. [15204803]
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