Stephen J. Schueler, M.D.

Overview Incidence Symptoms Evaluation Treatment specialist Outlook Underlying Cause Types adult childhood infantile

Decreased Alkaline Phosphatase Infantile

Infantile hypophosphatasia is the most common form of hypophosphatasia. Symptoms start before 6 months of age.

Symptoms of hypophosphatasia in infants include:

Less than 50% of infants survive the illness.

Last Updated: Mar 20, 2009 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Decreased Alkaline Phosphatase References
  1. Girschick HJ, Schneider P, Kruse K, Huppertz HI. Bone metabolism and bone mineral density in childhood hypophosphatasia. Bone. 1999 Sep;25(3):361-7. [10495141]
  2. Girschick HJ, Seyberth HW, Huppertz HI. Treatment of childhood hypophosphatasia with nonsteroidal antiinflammatory drugs. Bone. 1999 Nov;25(5):603-7. [10574582]
  3. Wendling D, Jeannin-Louys L, Kremer P, Fellmann F, Toussirot E, Mornet E. Adult hypophosphatasia. Current aspects. Joint Bone Spine. 2001 Mar;68(2):120-4. [11324927]
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