Stephen J. Schueler, M.D.

Overview Incidence Symptoms Evaluation Treatment specialist Outlook Underlying Cause Types adult childhood infantile

Decreased Alkaline Phosphatase Treatment

There is no cure for hypophosphatasia. Treatment for hypophosphatasia usually includes nonsteroidal anti-inflammatory medications, alkaline phosphatase replacement therapy, and surgery.

Treatment options for hypophosphatasia may include:

  • Nonsteroidal anti-inflammatory medications for hypophosphatasia
  • Alkaline phosphatase replacement therapy for hypophosphatasia
  • Surgery for hypophosphatasia:
    • To correct bone deformities caused by hypophosphatasia
    • To correct pseudofractures of the long bones
  • Avoid vitamin and mineral supplements for rickets. Excessive vitamin D can cause hypercalcemia and other side effects.
  • Avoidance of contact sports.

Decreased Alkaline Phosphatase Specialist

Physicians from the following specialties evaluate and treat hypophosphatasia:

Continue to Decreased Alkaline Phosphatase Outlook

Last Updated: Dec 16, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Decreased Alkaline Phosphatase References
  1. Girschick HJ, Schneider P, Kruse K, Huppertz HI. Bone metabolism and bone mineral density in childhood hypophosphatasia. Bone. 1999 Sep;25(3):361-7. [10495141]
  2. Girschick HJ, Seyberth HW, Huppertz HI. Treatment of childhood hypophosphatasia with nonsteroidal antiinflammatory drugs. Bone. 1999 Nov;25(5):603-7. [10574582]
  3. Wendling D, Jeannin-Louys L, Kremer P, Fellmann F, Toussirot E, Mornet E. Adult hypophosphatasia. Current aspects. Joint Bone Spine. 2001 Mar;68(2):120-4. [11324927]
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