The long-term treatment of coronary artery disease depends on the severity, the condition of the heart and the presence of other diseases.
| Angina Severity | Treatment Options |
| Stable / mild or moderate | Control of cardiac risk factors; drug therapy |
| Unstable / mild to moderate | Hospitalization; control of cardiac risk factors; drug therapy |
| Unstable / severe symptoms | Drug treatment; angioplasty; coronary artery bypass grafting |
General measures to treat coronary disease:
Medicines commonly used in coronary artery disease patients include:
- ACE Inhibitors:
- Lower blood pressure and reduce the work of the heart
- Aspirin:
- Thins the blood, in order lower the risk of blood clots in the coronary arteries
- Beta-blockers:
- Lower blood pressure and reduce the work of the heart

- Calcium channel blockers:
- Statins:
- Lower cholesterol and reduce inflammation inside the coronary arteries

- Clopidogrel (Plavix):
- Thins the blood, in order lower the risk of blood clots in the coronary arteries
- Nitrates:
- Open coronary arteries and let the heart work more efficiently