A newer class of drugs similar to ACE inhibitors is known as angiotensin II receptor blockers. These medications are usually prescribed for people who cannot take ACE inhibitors because of side effects. Most patients may benefit from a drug in this class or an ACE inhibitor, but will seldom need both.

These drugs work by blocking the binding of angiotensin II to type 1-angiotensin II receptors in the body. The effect is a reduction in the effects of the hormone angiotensin II. Angiotensin II plays a major role in the maintenance of blood pressure in the human body.

Common AR2 blockers:

• Candesartan (Atacand)
• Irbesartan (Avapro)
• Losartan (Cozaar)
• Telmisartan (Micardis)
• Valsartan (Diovan)
• Eprosartan (Teveten)
• Olmesartan (Benicar)