Congenital Brittle Bones Anatomy
To better understand osteogenesis imperfecta, it helps to understand bone anatomy.
The skeleton is a living structure that supports the entire body. Bone is made up of an outer shell of very dense bone that surrounds a honeycomb-like structure of softer bone. Bone mainly consists of protein and calcium. Without calcium, bone will become weak.
The human skeleton can be divided into two sections:
- Axial skeleton:
- Appendicular skeleton:
- A total of 126 bones including the pelvic girdle, limbs, feet and hands
Continue to Congenital Brittle Bones Genetics
- Chevrel G, Cimaz R. Osteogenesis imperfecta: new treatment options. Curr Rheumatol Rep. 2006 Dec;8(6):474-9. 
- Martin E, Shapiro JR. Osteogenesis imperfecta:epidemiology and pathophysiology. Curr Osteoporos Rep. 2007 Sep;5(3):91-7. 
- Rauch F, Glorieux FH. Treatment of children with osteogenesis imperfecta. Curr Osteoporos Rep. 2006 Dec;4(4):159-64.