Chronic Myelogenous Leukemia Treatment
Currently, there is no cure for chronic myelogenous leukemia. Treatment for chronic myelogenous leukemia usually includes medication that targets abnormal cancer cells and destroys them. Additional treatment for worsening chronic myelogenous leukemia includes interferon therapy, or chemotherapy and bone marrow transplant.
Chemotherapy drugs kill rapidly growing cancer cells. To perform a bone marrow transplant, chemotherapy is used to destroy the cells in the bone marrow first, and then bone marrow from a donor is transplanted into the patient's bone. Medications to control nausea are usually required during chemotherapy. The spleen may become enlarged as it removes abnormal cells from the bloodstream. In some cases, an enlarged spleen must be removed.
Treatment options for chronic myelogenous leukemia include:
- Narcotic pain medication:
- For moderate to severe pain
- For short term use only
- Nonsteroidal anti-inflammatory medications for pain:
- Ibuprofen (Motrin, Advil, Nuprin, NeoProfen)
- Ketoprofen (Actron, Orudis, Oruvail)
- Naproxen (Anaprox, Naprosyn, Aleve)
- Celecoxib (Celebrex)
- Medications for nausea and vomiting:
- Aprepitant (Emend)
- Dolasetron (Anzemet)
- Granisetron (Kytril)
- Metoclopramide (Reglan)
- Ondansetron (Zofran)
- Palonosetron (Aloxi)
- Prochlorperazine (Compazine, Compro)
- Chemotherapy for chronic myelogenous leukemia:
- Hydroxyurea (Hydrea)
- Busulfan (Myleran)
- Imatinib mesylate (Gleevec)
- Dasatinib (Sprycel)
- Nilotinib (Tasigna)
- Bone marrow transplant for chronic myelogenous leukemia
- Radiation therapy for chronic myelogenous leukemia
Chronic Myelogenous Leukemia Questions For Doctor
The following are some important questions to ask before and after the treatment of chronic myelogenous leukemia.
Questions to ask before treatment:
- What are my treatment options?
- Is surgery an option for me?
- What are the risks associated with treatment?
- Do I need to stay in the hospital?
- How long will I be in the hospital?
- What are the complications I should watch for?
- How long will I be on medication?
- What are the potential side effects of my medication?
- Does my medication interact with nonprescription medicines or supplements?
- Should I take my medication with food?
Questions to ask after treatment:
- Do I need to change my diet?
- Do I need to lose weight?
- Are there any medications or supplements I should avoid?
- When can I resume my normal activities?
- When can I return to work?
- What else can I do to reduce my risk for complications?
- How often will I need to see my doctor for checkups?
- What local support and other resources are available
Chronic Myelogenous Leukemia Specialist
Continue to Chronic Myelogenous Leukemia Home Care
- O'Brien S, Tefferi A, Valent P. Chronic myelogenous leukemia and myeloproliferative disease. Hematology (Am Soc Hematol Educ Program). 2004;:146-62. 
- Randolph TR. Chronic myelocytic leukemia--Part I: History, clinical presentation, and molecular biology. Clin Lab Sci. 2005 Winter;18(1):38-48. 
- Van Etten RA, Shannon KM. Focus on myeloproliferative diseases and myelodysplastic syndromes. Cancer Cell. 2004 Dec;6(6):547-52.