Stephen J. Schueler, M.D.

Overview Symptoms

Chronic Inflammatory Polyneuropathy Overview

What is chronic inflammatory polyneuropathy?
A person with chronic inflammatory polyneuropathy has nerve swelling and inflammation to the nerves outside of the brain or spinal cord that can lead to a loss of movement or sensation. Most with this disorder develop progressive weakness and impaired sensory function to the arms and legs. The symptoms of chronic inflammatory polyneuropathy are caused by damage to the myelin sheath, a substance that coats nerve fibers allowing them to conduct nerve impulses. Chronic inflammatory polyneuropathy is closely related to Guillain-Barre syndrome.

What are the symptoms of chronic inflammatory polyneuropathy?
Symptoms of chronic inflammatory polyneuropathy include facial weakness, difficulty using the extremities, weakness of the extremities, breathing difficulty, hoarseness, swallowing difficulty, bowel or bladder problems, joint pain, muscle atrophy, and loss of function or feeling in the muscles.

How does the doctor treat chronic inflammatory polyneuropathy?
Treatment of chronic inflammatory polyneuropathy depends on the severity of the symptoms. Corticosteroids may be used to help reduce inflammation. Other options include immunosuppressant drugs, intravenous immunoglobulin, and plasmapheresis. Physical therapy is important to improve muscle strength, function, and mobility.

Continue to Chronic Inflammatory Polyneuropathy Symptoms

Last Updated: Dec 7, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Chronic Inflammatory Polyneuropathy References
  1. Vallat JM, Sommer C, Magy L. Chronic inflammatory demyelinating polyradiculoneuropathy: diagnostic and therapeutic challenges for a treatable condition. Lancet Neurol. 2010 Apr;9(4):402-12. [20298964]
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