Stephen J. Schueler, M.D.

Overview Risk Factors Symptoms Evaluation Treatment questions for doctor specialist Home Care anorexia diet pain control side effects taking control warning signs Outlook Complications Underlying Cause Anatomy

Cholangiocarcinoma Underlying Cause

The cause of cholangiocarcinoma is unknown, but genetics may play a role. Gallstones, chronic viral hepatitis, and cirrhosis do not appear to be factors in the development of cholangiocarcinoma.

Genes control the functions inside a cell. Special genes control how cells divide and grow. Cancer occurs when the damaged genes stimulate the cell to multiply out of control. The exact cause for this damage is unknown.


  • DNA
  • Genes on chromosomes
  • Cancer cells
  • Cancer cell division

Continue to Cholangiocarcinoma Anatomy

Last Updated: Jun 24, 2008 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
Copyright DSHI Systems, Inc. Powered by: FreeMD - Your Virtual Doctor

PubMed Cholangiocarcinoma References
  1. Jones BA, Gores GJ. Hepatobiliary malignancy. Clin Liver Dis. 1998 May;2(2):437-49, xi-xii. [15560042]
  2. Lazaridis KN, Gores GJ. Cholangiocarcinoma. Gastroenterology. 2005 May;128(6):1655-67. [15887157]
  3. Thongprasert S. The role of chemotherapy in cholangiocarcinoma. Ann Oncol. 2005;16 Suppl 2:ii93-6. [15958484]
FreeMD is provided for information purposes only and should not be used as a substitute for evaluation and treatment by a physician. Please review our terms of use.