Nesiritide is a purified, natural hormone called human B-type natriuretic peptide, which is produced in the ventricles of the heart. Nesiritide causes veins and arteries to dilate and promotes renal excretion of sodium and water. These actions reduce stress on the weakened heart seen in patients with congestive heart failure. This allows the weakened heart to function more efficiently and improves patient symptoms.
Concurrent administration with ACE inhibitors and other vasodilators may cause low blood pressure.
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