Stephen J. Schueler, M.D.

Cardiac Failure AR2 Blockers

A newer class of drugs similar to ACE inhibitors is known as angiotensin II receptor blockers. These medications are usually prescribed for people who cannot take ACE inhibitors because of side effects. Most patients may benefit from a drug in this class or an ACE inhibitor, but will seldom need both.

These drugs work by blocking the binding of angiotensin II to type 1-angiotensin II receptors in the body. The effect is a reduction in the effects of the hormone angiotensin II. Angiotensin II plays a major role in the maintenance of blood pressure in the human body.

Common AR2 blockers:

Continue to Cardiac Failure Beta-Blockers

Last Updated: Dec 8, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Cardiac Failure References
  1. Bibbins-Domingo K, Lin F, Vittinghoff E, Barrett-Connor E, Hulley SB, Grady D, Shlipak MG. Predictors of heart failure among women with coronary disease. Circulation. 2004 Sep 14;110(11):1424-30. [1535349]
  2. Chen QM, Tu VC. Apoptosis and heart failure: mechanisms and therapeutic implications. Am J Cardiovasc Drugs. 2002;2(1):43-57. [14727998]
  3. Ebinger MW, Krishnan S, Schuger CD. Mechanisms of ventricular arrhythmias in heart failure. Curr Heart Fail Rep. 2005 Sep;2(3):111-7. [16138946]
  4. Mitchell J, Taylor A. Congestive heart failure in women. J Fam Pract. 2005 Jul;Suppl:6-7. [16134558]
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