Stephen J. Schueler, M.D.

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Cancer Squamous Cell Underlying Cause

The cause of squamous cell carcinoma is unknown, but exposure to the sun and genetics play a role in determining risk.

Genes control all of the functions inside a cell. Special genes control how cells divide and grow. Cancer occurs when the damaged genes stimulate the cell to multiply out of control. The exact cause for this damage is unknown.


  • DNA
  • Genes on chromosomes
  • Cancer cells
  • Cancer cell division

Continue to Cancer Squamous Cell Anatomy

Last Updated: Jun 22, 2009 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Cancer Squamous Cell References
  1. Campbell FA, Gupta G. The management of non-melanoma skin cancer. Hosp Med. 2005 May;66(5):288-93. [15920859]
  2. Clayman GL, Lee JJ, Holsinger FC, et al. Mortality risk from squamous cell skin cancer. J Clin Oncol. 2005 Feb 1;23(4):759-65. [15681519]
  3. Einspahr JG, Bowden GT, Alberts DS. Skin cancer chemoprevention: strategies to save our skin. Recent Results Cancer Res. 2003;163:151-64; discussion 264-6. [12903851]
  4. Glass AG, Hoover RN. The emerging epidemic of melanoma and squamous cell skin cancer. JAMA. 1989 Oct 20;262(15):2097-100. [2795783]
  5. Yuspa SH. The pathogenesis of squamous cell cancer: lessons learned from studies of skin carcinogenesis. J Dermatol Sci. 1998 May;17(1):1-7. [9651822]
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