Stephen J. Schueler, M.D.

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Cancer of the Ovary Underlying Cause

The cause for ovarian cancer is unknown, but genetics seem to play a role in determining risk.

Genes control all of the functions inside a cell. Special genes control how cells divide and grow. Cancer occurs when the damaged genes stimulate the cell to multiply out of control. The exact cause for this damage is unknown.


  • DNA
  • Genes on chromosomes
  • Cancer cells
  • Cancer cell division

Continue to Cancer of the Ovary Anatomy

Last Updated: Dec 22, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Cancer of the Ovary References
  1. Boente MP, Hamilton TC, Godwin AK, Buetow K, Kohler MF, Hogan WM, Berchuck A, Young RC. Early ovarian cancer: a review of its genetic and biologic factors, detection, and treatment. Curr Probl Cancer. 1996 Mar-Apr;20(2):83-137. [8731031]
  2. Johnston SR. Ovarian cancer: review of the National Institute for Clinical Excellence (NICE) guidance recommendations. Cancer Invest. 2004;22(5):730-42. [15581055]
  3. Rosen B, Kwon J, Fung Kee Fung M, Gagliardi A, Chambers A; Cancer Care Ontario's Practice Guidelines Initiative Gynecology Cancer Disease Site Group. Systematic review of management options for women with a hereditary predisposition to ovarian cancer. Gynecol Oncol. 2004 May;93(2):280-6. [1509993]
  4. Wolf JK, Jenkins AD. Gene therapy for ovarian cancer (review). Int J Oncol. 2002 Sep;21(3):461-8. [12168087]
  5. Young M, Plosker GL. Paclitaxel: a pharmacoeconomic review of its use in the treatment of ovarian cancer. Pharmacoeconomics. 2001;19(12):1227-59. [11772158]
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