Stephen J. Schueler, M.D.

Overview Incidence Risk Factors Symptoms Evaluation staging Treatment questions for doctor specialist Outlook Underlying Cause Anatomy

Cancer of the Lung Lining Underlying Cause

As many as 80% of those with mesothelioma have had a long-term exposure to asbestos. Asbestos may play a role in damaging the cells that line the lung, which then leads to cancer.

The cause for mesothelioma is unknown, but genetics may also play a role in determining risk.

Genes control the functions inside a cell. Special genes control how cells divide and grow. Cancer occurs when the damaged genes stimulate the cell to multiply out of control. The exact cause for this damage is unknown.


  • DNA
  • Genes on chromosomes
  • Cancer cells
  • Cancer cell division

Continue to Cancer of the Lung Lining Anatomy

Last Updated: Jun 10, 2009 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Cancer of the Lung Lining References
  1. Laden F, Stampfer MJ, Walker AM. Lung cancer and mesothelioma among male automobile mechanics: a review. Rev Environ Health. 2004 Jan-Mar;19(1):39-61. [15186039]
  2. Maziak DE, Gagliardi A, Haynes AE, Mackay JA, Evans WK; Cancer Care Ontario Program in Evidence-based Care Lung Cancer Disease Site Group. Surgical management of malignant pleural mesothelioma: a systematic review and evidence summary. Lung Cancer. 2005 May;48(2):157-69. [15829316]
  3. van Ruth S, Baas P, Zoetmulder FA. Surgical treatment of malignant pleural mesothelioma: a review. Chest. 2003 Feb;123(2):551-61. [12576380]
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