Stephen J. Schueler, M.D.

Cancer of the Anus Underlying Cause

The exact cause of anal cancer is unknown, but genetics may play a role in the determination of risk.

Genes control the functions inside a cell. Special genes control how cells divide and grow. Cancer occurs when the damaged genes stimulate the cell to multiply out of control. The exact cause for this damage is unknown.


  • DNA
  • Genes on chromosomes
  • Cancer cells
  • Cancer cell division

Continue to Cancer of the Anus Anatomy

Last Updated: Mar 10, 2009 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Cancer of the Anus References
  1. Clark MA, Hartley A, Geh JI. Cancer of the anal canal. Lancet Oncol. 2004 Mar;5(3):149-57. [15003197]
  2. Sato H, Koh PK, Bartolo DC. Management of anal canal cancer. Dis Colon Rectum. 2005 Jun;48(6):1301-15. [15793642]
  3. Welton ML, Sharkey FE, Kahlenberg MS. The etiology and epidemiology of anal cancer. Surg Oncol Clin N Am. 2004 Apr;13(2):263-75. [15137956]
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