Bowed Legs Paget's Disease Underlying Cause
The exact cause of Paget's disease is unknown.
Bones are constantly changing. Old bone is removed by specialized bone cells, called osteoclasts, and new bone is laid down in its place by specialized cells, called osteoblasts. This process is known as bone remodeling. During childhood and adolescence the body is producing new bone faster than it is removing old bone. As a result, the skeletal system grows and becomes stronger. This usually reaches a peak between the age of 20 and 30.
Person's with Paget's have abnormal bone remodeling, which results in deformities of the bones. The pelvis, lumbar spine, femur, thoracic spine, sacrum, skull, tibia, and humerus are the most commonly affected bones.
Continue to Bowed Legs Paget's Disease Anatomy
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