The evaluation of aspergillosis begins with a medical history and physical examination.

Physical findings in those with aspergillosis may include:

• Wheezing
• Increased breathing rate
• Abnormalities of the retina if eye disease is present

The diagnosis of aspergillosis must be confirmed through testing.

Tests for aspergillosis may include:

• Complete blood count
• Sputum culture
• Chest x-ray
• Bronchoscopy
• Thoracoscopy
• Lung biopsy
• Serologic tests that measure the level of aspergillus antibody in the bloodstream
• Serum immunoglobulins