AODM Underlying Cause
Insulin is a hormone that controls the level of the sugar, glucose, in the bloodstream. Insulin reduces blood glucose levels by stimulating cells in the body to utilize glucose for energy. Insulin is produced by special cells, called beta cells, within the pancreas.
In type 2 diabetes, the cells do not respond properly to insulin, and glucose levels rise in the bloodstream.
Causes of type 2 diabetes include:
- Hereditary factors:
- Tends to run in families
Continue to AODM Anatomy
- Davis RE, Morrissey M, Peters JR, Wittrup-Jensen K, Kennedy-Martin T, Currie CJ. Impact of hypoglycaemia on quality of life and productivity in type 1 and type 2 diabetes. Curr Med Res Opin. 2005 Sep;21(9):1477-83. 
- Lebovitz HE. Type 2 diabetes: an overview. Clin Chem. 1999 Aug;45(8 Pt 2):1339-45. 
- Nagaya T, Yoshida H, Takahashi H, Kawai M. Increases in body mass index, even within non-obese levels, raise the risk for Type 2 diabetes mellitus: a follow-up study in a Japanese population. Diabet Med. 2005 Aug;22(8):1107-11. 
- Patja K, Jousilahti P, Hu G, Valle T, Qiao Q, Tuomilehto J. Effects of smoking, obesity and physical activity on the risk of type 2 diabetes in middle-aged Finnish men and women. J Intern Med. 2005 Oct;258(4):356-62. 
- Ratner RE. Type 2 diabetes mellitus: the grand overview. Diabet Med. 1998;15 Suppl 4:S4-7.