The Centers for Disease Control in the US recommends treatment with two antibiotics:

• Ciprofloxacin and doxycycline

These medications are initially given through an intravenous line in the hospital.

Additional antibiotics may include:

• Chloramphenicol
• Clarithromycin
• Clindamycin
• Imipenem and Cilastatin
• Penicillin
• Rifampin
• Vancomycin

Most mild, cutaneous cases of anthrax will respond to oral doses of penicillin or doxycycline. Cipro is recommended by the CDC as the best drug for cutaneous anthrax, but may not be necessary in all cases.