Stephen J. Schueler, M.D.

Overview Symptoms Evaluation Treatment specialist Home Care warning signs Prevention Outlook Underlying Cause

Angioedema Hereditary Underlying Cause

The cause of hereditary angioedema is an abnormal gene that results in low levels of C1 inhibitor protein. C1 inhibitor protein prevents episodes of inflammation in the body. When levels of the protein are low, inflammation occurs much more easily in all tissues of the body.

Factors that may trigger episodes of swelling in those with hereditary angioedema include:

Last Updated: Aug 20, 2007 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
Copyright DSHI Systems, Inc. Powered by: FreeMD - Your Virtual Doctor

PubMed Angioedema Hereditary References
  1. Davis AE 3rd. The pathophysiology of hereditary angioedema. Clin Immunol. 2005 Jan;114(1):3-9. [1559640]
  2. Nzeako UC, Frigas E, Tremaine WJ. Hereditary angioedema: a broad review for clinicians. Arch Intern Med. 2001 Nov 12;161(20):2417-29. [11700154]
  3. Zuraw BL. Current and future therapy for hereditary angioedema. Clin Immunol. 2005 Jan;114(1):10-6. [15596404]
FreeMD is provided for information purposes only and should not be used as a substitute for evaluation and treatment by a physician. Please review our terms of use.