Overview Symptoms Evaluation Treatment specialist Home Care warning signs Prevention Outlook Underlying Cause
Angioedema Hereditary Evaluation
- Skin swelling is most common in the face and around the eyes
- Angioedema can interfere with breathing when it causes swelling in the mouth, tongue, or throat.
- Genital swelling
Testing may be necessary to determine the underlying cause of angioedema.
Tests that may be used to evaluate hereditary angioedema include:
- Complete blood count
- C1 esterase blood level:
- An important test for anyone who may have hereditary angioedema. Low levels of this enzyme will confirm this diagnosis.
- Allergy testing may include one or more of the following:
- Aquagenic: a test used to detect water-induced urticaria.
- Delayed Pressure: this test involves the placement of a 5 to 10 pound object on the skin for 10 to 15 minutes and then observing the skin's reaction for the next three hours.
- Dermatographism: a test involving the skin's reaction upon being scratched by a tongue blade; the course of the tongue blade is seen in a welt-like pattern on the skin
- Ice-Cube Test: touching ice to the skin can trigger cold-induced urticaria in some individuals.
- Methacholine Test: this is a test that is used to identify cholinergic or exercise-induced urticaria.
- Skin testing: the most common test where small amounts of allergens are placed into the skin.
Continue to Angioedema Hereditary Treatment
PubMed Angioedema Hereditary References
- Davis AE 3rd. The pathophysiology of hereditary angioedema. Clin Immunol. 2005 Jan;114(1):3-9. 
- Nzeako UC, Frigas E, Tremaine WJ. Hereditary angioedema: a broad review for clinicians. Arch Intern Med. 2001 Nov 12;161(20):2417-29. 
- Zuraw BL. Current and future therapy for hereditary angioedema. Clin Immunol. 2005 Jan;114(1):10-6.