Anemia Pernicious Underlying Cause
Pernicious anemia is caused by decreased levels of intrinsic factor, which is an enzyme that helps the body absorb vitamin B-12. The body requires vitamin B-12 in order to make red blood cells: without it, low levels of red blood cells result in anemia.
Causes of low intrinsic factor include:
Continue to Anemia Pernicious Anatomy
- Carmel R. Prevalence of undiagnosed pernicious anemia in the elderly. Arch Intern Med. 1996 May 27;156(10):1097-100. 
- Lederle FA. Oral cobalamin for pernicious anemia: back from the verge of extinction. J Am Geriatr Soc. 1998 Sep;46(9):1125-7. 
- Wickramasinghe SN. The wide spectrum and unresolved issues of megaloblastic anemia. Semin Hematol. 1999 Jan;36(1):3-18.