The evaluation of amyotrophic lateral sclerosis begins with a history and physical exam.

Physical findings in those with amyotrophic lateral sclerosis include:

• Muscle weakness
• Muscle wasting
• Muscle spasms

The diagnosis of amyotrophic lateral sclerosis requires testing.

Testing for amyotrophic lateral sclerosis may include:

• EEG
• EMG
• Nerve conduction studies
• Tensilon test
• Muscle biopsy
• Nerve biopsy
• CT scan of the brain
• MRI scan of the brain