Life-long treatment is required for amyloidosis because there is no cure for the disease. Treatment for amyloidosis is directed at reducing the production of the amyloid protein, by using medications that suppress the immune system, which normally fights infection. Additional treatment is directed at managing the major complications, such as congestive heart failure, liver failure and kidney disease. Depending on which organs have been affected by the disease, additional treatment may require surgery to repair damaged joints, removal of the spleen, and organ transplants.
Treatment of amyloidosis symptoms and complications may include:
- Chemotherapy for amyloidosis:
- Prednisone (Deltasone, Orasone, Meticorten)
- Melphalan (Alkeran) and prednisone (Deltasone, Orasone, Meticorten)
- Bortezomib (Velcade)
- Thalidomide (Thalomid)
- Lenalidomide (Revlimid)
- Surgical removal of the spleen
- Congestive heart failure treatment:
- Kidney disease treatment:
- Use of tumor necrosis factor inhibitors
- Use of interleukin-1 inhibitors
- Kidney dialysis
- Clears wastes from the bloodstream
- Peritoneal dialysis
- Similar to kidney dialysis by clearing wastes from the bloodstream
- Kidney transplant for kidney failure
- Liver transplant for liver failure
Amyloidosis Questions For Doctor
The following are some important questions to ask before and after the treatment of amyloidosis.
Questions to ask before treatment:
- What are my treatment options?
- Is surgery an option for me?
- What are the risks associated with treatment?
- Do I need to stay in the hospital?
- How long will I be in the hospital?
- What are the complications I should watch for?
- How long will I be on medication?
- What are the potential side effects of my medication?
- Does my medication interact with nonprescription medicines or supplements?
- Should I take my medication with food?
Questions to ask after treatment:
- Do I need to change my diet?
- Do I need to lose weight?
- Are there any medications or supplements I should avoid?
- When can I resume my normal activities?
- When can I return to work?
- How often will I need to see my doctor for checkups?
- What local support and other resources are available?
Physicians from the following specialties evaluate and treat amyloidosis:
Continue to Amyloidosis Home Care
- Benson MD: Aging, amyloid, and cardiomyopathy. N Engl J Med 1997 Feb 13; 336(7): 502-4. 
- Gertz MA, Lacy MQ, Dispenzieri A: Amyloidosis: recognition, confirmation, prognosis, and therapy. Mayo Clin Proc 1999 May; 74(5): 490-4. 
- Pepys MB. Amyloidosis. Annu Rev Med. 2005 Aug 24.