Stephen J. Schueler, M.D.

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Allergic Angioedema Evaluation

The evaluation of angioedema begins with a history and physical exam.

Physical findings in those with angioedema may include:

Testing is necessary to determine the underlying cause for angioedema.

Tests for angioedema may include:
  • Complete blood count
  • Serum C1 esterase level
  • Allergy testing may include one or more of the following:
    • Aquagenic: tests for a reaction to water
    • Delayed Pressure: tests for a reaction placing pressure on the skin
    • Dermatographism: tests for a reaction to scraping the skin
    • Ice-Cube test: tests for a reaction to cold
    • Methacholine test: tests for a reaction to exercise
    • Skin testing: small amounts of allergens are injected into the skin

For more information:

Continue to Allergic Angioedema Treatment

Last Updated: Nov 16, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Allergic Angioedema References
  1. Baxi S, Dinakar C. Urticaria and angioedema. Immunol Allergy Clin North Am. 2005 May;25(2):353-67, vii. [15878460]
  2. Gompels MM, Lock RJ, Abinun M, Bethune CA, Davies G, Grattan C, Fay AC, Longhurst HJ, Morrison L, Price A, Price M, Watters D. C1 inhibitor deficiency: consensus document. Clin Exp Immunol. 2005 Mar;139(3):379-94. [15730382]
  3. Varadarajulu S. Urticaria and angioedema. Controlling acute episodes, coping with chronic cases. Postgrad Med. 2005 May;117(5):25-31. [15948365]
  4. Zuraw BL. Current and future therapy for hereditary angioedema. Clin Immunol. 2005 Jan;114(1):10-6. [15596404]
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