Because a person with agammaglobulinemia is missing antibodies, treatment includes replacing the antibodies, called immunoglobulins, in the bloodstream. Antibodies are given through an intravenous (IV) line every 3 to 4 weeks. Because agammaglobulinemia weakens the immune system, bacterial infections require early and aggressive treatment with antibiotics. A person with agammaglobulinemia should not receive live vaccines for common viral infections, such as measles, mumps and rubella, because they may cause infection.
Specific treatment for agammaglobulinemia may include:
- Intravenous immune globulin (IVIG) therapy for agammaglobulinemia:
- Helps boost the immune system, by replacing lost antibodies
- Antibiotic therapy for infections:
- Early treatment is very important, in order to avoid severe infections.
Continue to Agammaglobulinemia Complications
- Buckley RH: Pulmonary complications of primary immunodeficiencies. Paediatr Respir Rev 2004; 5 (Suppl A): S225-33. 
- Conley ME: Early defects in B cell development. Curr Opin Allergy Clin Immunol 2002; 2: 517-22. 
- Dalal I, Reid B, Nisbet-Brown E, Roifman CM: The outcome of patients with hypogammaglobulinemia in infancy and early childhood. J Pediatr 1998 Jul; 133(1): 144-6. 
- Kidon MI, Handzel ZT, Schwartz R et al.: Symptomatic hypogammaglobulinemia in infancy and childhood: clinical outcome and in vitro immune responses. BMC Fam Pract 2004; 5: 23. 
- Lawrence T, Puel A, Reichenbach J, Ku CL, Chapgier A, Renner E, Minard-Colin V, Ouachee M, Casanova JL. Autosomal-dominant primary immunodeficiencies. Curr Opin Hematol. 2005 Jan;12(1):22-30.