Stephen J. Schueler, M.D.

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Agammaglobulinemia Evaluation

The evaluation of agammaglobulinemia begins with a history and physical examination.

Usually, the physical exam is normal in someone with agammaglobulinemia.

Testing is necessary to make the diagnosis of agammaglobulinemia.

Tests that may be used to evaluate agammaglobulinemia include:

  • Serum immunoelectrophoresis
  • Serum IgG levels
  • Serum IgA levels
  • Serum IgM levels

Continue to Agammaglobulinemia Treatment

Last Updated: Nov 9, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Agammaglobulinemia References
  1. Buckley RH: Pulmonary complications of primary immunodeficiencies. Paediatr Respir Rev 2004; 5 (Suppl A): S225-33. [14980276]
  2. Conley ME: Early defects in B cell development. Curr Opin Allergy Clin Immunol 2002; 2: 517-22. [14752335]
  3. Dalal I, Reid B, Nisbet-Brown E, Roifman CM: The outcome of patients with hypogammaglobulinemia in infancy and early childhood. J Pediatr 1998 Jul; 133(1): 144-6. [9672529]
  4. Kidon MI, Handzel ZT, Schwartz R et al.: Symptomatic hypogammaglobulinemia in infancy and childhood: clinical outcome and in vitro immune responses. BMC Fam Pract 2004; 5: 23. [15498106]
  5. Lawrence T, Puel A, Reichenbach J, Ku CL, Chapgier A, Renner E, Minard-Colin V, Ouachee M, Casanova JL. Autosomal-dominant primary immunodeficiencies. Curr Opin Hematol. 2005 Jan;12(1):22-30. [15604887]
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