Stephen J. Schueler, M.D.

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Adult Still's Disease Anatomy

To better understand adult still's disease, it helps to understand the anatomy of the joints.

The bones in all joints have a smooth lining called articular cartilage. Cartilage provides a gliding surface to help joints move. All joints are lubricated with a slippery liquid known as synovial fluid.

Joint cartilage may break down due to inflammation, overuse or injury. This can result in the bones of a joint making contact. This in turn causes abnormal bone growth, more inflammation, pain and stiffness.

Anatomy of joints commonly affected by osteoarthritis:

  • Cervical spine
  • Knee
  • Lumbar spine
  • Hip
  • Wrist and hand
  • Hand joints affected by osteoarthritis

Last Updated: Nov 9, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Adult Still's Disease References
  1. Husni ME, Maier AL, Mease PJ, Overman SS, Fraser P, Gravallese EM, Weinblatt ME. Etanercept in the treatment of adult patients with Still's disease. Arthritis Rheum. 2002 May;46(5):1171-6. [12115220]
  2. Kadar J, Petrovicz E. Adult-onset Still's disease. Best Pract Res Clin Rheumatol. 2004 Oct;18(5):663-76. [15454125]
  3. Mert A, Ozaras R, Tabak F, Bilir M, Ozturk R, Ozdogan H, Aktuglu Y. Fever of unknown origin: a review of 20 patients with adult-onset Still's disease. Clin Rheumatol. 2003 May;22(2):89-93. [12740670]
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