Stephen J. Schueler, M.D.

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Acute Lymphocytic Leukemia Pain in Children

Common medications used at home for pain in children with acute lymphocytic leukemia include:

  • Acetaminophen: often the best drug for mild pain in leukemia patients
  • Ibuprofen: may increase the risk of bleeding in leukemia
  • Naproxen (must be 13 or older): may increase the risk of bleeding
  • Narcotics and prescription medicines

Acetaminophen
  • Acetaminophen decreases fever and pain, but does not help inflammation.
  • Dosing is 10-15 mg per kilogram (5-7 mg per pound) of body weight every 4-6 hours, up to the adult dose.
  • Do not exceed the maximum daily dose.
  • Acetaminophen products come in various strengths. Always follow the package instructions.
  • Avoid this drug in children with liver disease or an allergy to acetaminophen.
  • Common acetaminophen products include Tylenol, Panadol and many others.

Ibuprofen
  • Ibuprofen decreases pain, fever and inflammation.
  • It is a nonsteroidal anti-inflammatory medication (NSAID).
  • Dosing for children over 6 months of age is 7-10 mg per kilogram (4-5 mg per pound) of body weight every 6 hours, up to the adult dose.
  • Do not exceed the maximum daily dose.
  • Always follow the package instructions.
  • Ask your doctor first if it is OK to take this medicine.
  • Brand names include Advil, Motrin and Nuprin.

Naproxen

Continue to Acute Lymphocytic Leukemia Side Effects

Last Updated: Nov 9, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Acute Lymphocytic Leukemia References
  1. Alderton LE, Spector LG, et al. Child and maternal household chemical exposure and the risk of acute leukemia in children with Down's syndrome: a report from the Children's Oncology Group. Am J Epidemiol. 2006 Aug 1;164(3):212-21. [16760223]
  2. Fulcher JW, Allred TJ, et al. Granular acute lymphoblastic leukemia in adults: report of a case and review of the literature. South Med J. 2006 Aug;99(8):894-7. [16929890]
  3. Haferlach T, Kern W, Schnittger S, Schoch C. Modern diagnostics in acute leukemias. Crit Rev Oncol Hematol. 2005 Nov;56(2):223-34. [16213152]
  4. Pui CH, Pei D, Sandlund JT, et al. Risk of adverse events after completion of therapy for childhood acute lymphoblastic leukemia. J Clin Oncol. 2005 Nov 1;23(31):7936-41. [16258093]
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