Acute Intermittent Porphyria
Definition
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Risk Factors
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Acute Intermittent Porphyria Treatment
General treatment for acute intermittent
porphyria
includes:
Avoid medications that trigger
porphyria
.
Do not take
iron supplements
.
Do not drink alcohol.
Avoid fasting.
Avoid sun exposure.
Eat a high carbohydrate diet.
Take
vitamin A
supplements.
Porphyria
clinical trials
Treatment for a severe attack of acute intermittent
porphyria
may include:
Intravenous fluids
High doses of glucose
Hematin:
Reduces the production of
porphyrins
Anticonvulsant medications
for
seizures
:
Clonazepam
Gabapentin
Supplemental oxygen
Splenectomy
Removal of the spleen
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Acute Intermittent Porphyria Treatment: Specialist
Related Topics:
Depression
Porphyria cutanea tarda
Porphyria
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Last Updated: Mar 11, 2008
References
Authors:
Stephen J. Schueler, MD
;
John H. Beckett, MD
;
D. Scott Gettings, MD
Copyright 1989-2008
DSHI Systems, Inc.
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Acute Intermittent Porphyria References:
Anderson KE, Bloomer JR, Bonkovsky HL, Kushner JP, Pierach CA, Pimstone NR, Desnick RJ. Recommendations for the diagnosis and treatment of the acute porphyrias. Ann Intern Med. 2005 Mar 15;142(6):439-50.
Badminton MN, Elder GH. Management of acute and cutaneous porphyrias. Int J Clin Pract. 2002 May;56(4):272-8.
Elder GH, Hift RJ. Treatment of acute porphyria. Hosp Med. 2001 Jul;62(7):422-5.
Gonzalez-Arriaza HL, Bostwick JM. Acute porphyrias: a case report and review. Am J Psychiatry. 2003 Mar;160(3):450-9.
Kauppinen R. Porphyrias. Lancet. 2005 Jan 15-21;365(9455):241-52.
Sassa S. Diagnosis and therapy of acute intermittent porphyria. Blood Rev. 1996 Mar;10(1):53-8.
