The evaluation of acute glomerulonephritis begins with a medical history and physical examination.

Physical findings in those with acute glomerulonephritis may include:

• Confusion
• Lethargy
• Excessive sleepiness
• Dry skin
• Pale skin
• Caused by anemia
• Loss of muscle tissue
• Muscles become smaller
• Leg swelling
• Foot swelling (bilateral)
• Facial swelling
• Worse around the eyes
• Enlargement of the liver
• High blood pressure

Blood and urine tests are required to make the diagnosis of acute glomerulonephritis.

Tests that may be used to evaluate acute glomerulonephritis include:

• Serum calcium level
• Serum phosphate level
• Complete blood count
• Erythropoietin blood levels
• Kidney profile: includes sodium and potassium levels
• Urinalysis
• 24 hour urine for creatinine clearance

Additional tests that may be used to evaluate the kidneys include:

• Abdominal ultrasound
• Abdominal CT scan
• Intravenous pyelogram
• Kidney biopsy
• MRI scan of the abdomen
• Renal arteriogram
• Kidney biopsy