Stephen J. Schueler, M.D.

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Acute Demyelinating Polyneuropathy Underlying Cause

Guillain-Barre syndrome is caused by a malfunction of the immune system, which fights infection. The immune system mistakenly attacks the nerves that branch off the spinal cord.

This leaves the nerves unable to correctly transmit information to, and from, the brain. The cause of the immune system malfunction is unknown. Guillain-Barre syndrome tends to occur after a stressful event, such as an infection or surgery.

Last Updated: Mar 18, 2009 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Acute Demyelinating Polyneuropathy References
  1. Awong IE, Dandurand KR, Keeys CA, Maung-Gyi FA: Drug-associated Guillain-Barre syndrome: a literature review. Ann Pharmacother 1996 Feb; 30(2): 173-80. [8835052]
  2. Hughes RA, Wijdicks EF, Benson E, Cornblath DR, Hahn AF, Meythaler JM, Sladky JT, Barohn RJ, Stevens JC; Multidisciplinary Consensus Group. Supportive care for patients with guillain-barre syndrome. Arch Neurol. 2005 Aug;62(8):1194-8. [16087757]
  3. van Doorn PA. Treatment of Guillain-Barre syndrome and CIDP. J Peripher Nerv Syst. 2005 Jun;10(2):113-27. [15958124]
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