Actinomycosis usually requires treatment with antibiotics for 6 to 12 months. Some lesions may require incision and drainage, which allows infected tissue to drain from the site of the infection. With early treatment, the infection resolves completely.
Treatment for actinomycosis may include:
- Antibiotics for actinomycosis:
- Doxycycline (Vibramycin)
- Clindamycin (Cleocin)
- Amoxicillin and clavulanic acid (Augmentin)
- Ceftriaxone (Rocephin)
- Imipenem and cilastatin (Primaxin)
- Surgery for actinomycosis:
- Incision and drainage
- Removal of infected tissue
Incision and drainage of a skin abscess includes:
- The skin is sterilized using rubbing alcohol or an antibacterial soap.
- A local anesthetic is injected into the tissues surrounding the abscess.
- An incision is made with a scalpel.
- Pus is drained from the abscess.
- The abscess cavity is flushed clean.
- In some cases, a rubber drain or a strip of sterile gauze is packed inside the abscess cavity.
- The gauze or drain placed inside the abscess cavity is usually removed 24-36 hours later.
Physicians from the following specialties evaluate and treat actinomycosis:
Continue to Actinomycosis Home Care
- Felz MW, Smith MR. Disseminated actinomycosis: multisystem mimicry in primary care. South Med J. 2003 Mar;96(3):294-9. 
- Funke G, von Graevenitz A: Infections due to Actinomyces neuii (former "CDC coryneform group 1" bacteria). Infection 1995 Mar-Apr; 23(2): 73-5. 
- Smego RA Jr, Foglia G: Actinomycosis. Clin Infect Dis 1998 Jun; 26(6): 1255-61. 
- Sudhakar SS, Ross JJ. Short-term treatment of actinomycosis: two cases and aClin Infect Dis. 2004 Feb 1;38(3):444-7.