The evaluation of acromegaly begins with a medical history and physical examination.

Physical findings in someone with acromegaly include:

• Enlarged facial bones
• Enlarged hands and feet
• Enlargement of the jaw
• Thickening of the skin
• Widely spaced teeth
• Widened fingers and toes

Tests are required to make the diagnosis of acromegaly.

Tests that may be used to evaluate acromegaly include:

• Serum growth hormone level
• Growth hormone suppression test
• Kidney profile
• Glucose tolerance test
• Cervical spine x-rays
• Brain CT scanning
• Brain MRI scanning